Angiogenic Factors and Preeclampsia
نویسندگان
چکیده
منابع مشابه
Angiogenic Factors in Preeclampsia
Preeclampsia is one of the most frequently encountered hypertensive complication of pregnancy that affect ≈5% of pregnant women worldwide. It is often characterized by new onset of hypertension and proteinuria, usually during the last trimester of pregnancy, and is commonly associated with edema and hyperuricemia. Preeclampsia occurs only in the presence of the placenta, even when there is no f...
متن کاملAngiogenic Factors in Preeclampsia
Preeclampsia is one of the most frequently encountered hypertensive complication of pregnancy that affect ≈5% of pregnant women worldwide. It is often characterized by new onset of hypertension and proteinuria, usually during the last trimester of pregnancy, and is commonly associated with edema and hyperuricemia. Preeclampsia occurs only in the presence of the placenta, even when there is no f...
متن کاملAngiogenic factors in preeclampsia and related disorders.
During fetal development, the human placenta undergoes high levels of both angiogenesis and vasculogenesis. Additionally, the developing placenta undergoes a process of vascular mimicry (referred to as pseudovasculogenesis) as cytotrophoblasts convert from an epithelial to an endothelial phenotype. The initiation, maturation, and maintenance of the placental vasculature are of critical importan...
متن کاملAngiogenic factors in the pathogenesis of preeclampsia.
Preeclampsia affects 5-10% of pregnancies and is responsible for substantial maternal and neonatal morbidity and mortality. It is believed to be a two-stage disease with an initial placental trigger with no maternal symptoms followed by a maternal syndrome characterized by hypertension, proteinuria, and endothelial dysfunction. The first stage is thought to be due to shallow cytotrophoblast inv...
متن کاملCirculating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Preeclampsia is a major cause of maternal, fetal, and neonatal mortality worldwide. Although the etiology of preeclampsia is still unclear, recent studies suggest that its major phenotypes, high blood pressure and proteinuria, are due in part to excess circulating soluble fms-like tyrosine kinase-1 concentrations. Soluble fms-like tyrosine kinase-1 is an endogenous antiangiogenic protein that i...
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ژورنال
عنوان ژورنال: Seminars in Nephrology
سال: 2011
ISSN: 0270-9295
DOI: 10.1016/j.semnephrol.2010.10.004